Susan Merenstein, Pharmacist/Owner
Our Phytocannabinoid-Rich (PCR) Soft Gels are created with our proprietary water-soluble PCR hemp oil, along with other minor phytocannabinoids and naturally present terpenes. This product contains 10mg or 25mg of phytocannabinoids per soft gel and is designed to have optimum bioavailability.
The proprietary water-soluble formulation inside these soft gels is composed of a nanoemulsion-based delivery system where the high surface area of cannabinoid droplets maximizes in-vivo absorption and the resulting bioavailability is much higher than cannabinoids delivered in oil form. The enhanced and consistent absorption (despite fed vs. faster state) leads to predictable biological response and improved efficacy.
Small water-soluble softgel capsules that are taken orally with food. Water-soluble products are better absorbed than oil-based products. - Folium Biosciences
The patent pending water soluble formulation is a nanoemulsion based delivery system. The cannabinoid emulsion droplets range from 10-50 nm in size, maximizing the surface area for in-vivo absorption. The resulting bioavailability is 3-5 times higher than cannabinoids delivered in oil, leading to enhanced biological response. - Folium Biosciences
Organically Farmed in accordance with Industrial Regulations (Reg. #69763)
Hydrogenated Water and Supercritical CO2 Extraction Process – CO2 extraction allows the operator to tune the extraction using the process parameters (pressure, temperature, time, etc.) to extract specific compounds most efficiently. Ethanol extraction is less specific and will result in a lot of terpenes, waxes, and chlorophyll with your target compound.
General CBD Serving Guidelines: Start LOW & Go SLOW!
Less is more! By starting low and slowly increasing until you find your personal balance or homeostasis, you may get optimal benefits without wasting money on excess CBD.
mgs, mLs, 600, 1200, 3000 what does it all mean?
• mg stands for milligrams - The unit of weight of CBD per bottle.
• mL stands for milliliter - The unit of volume of liquid per bottle.
• mg/mL = Concentration. How much CBD (weight) is in how much liquid (volume)?
• The number next to “mg” on the bottle is a total amount of CBD (by weight) in that bottle.
Each serving is based on that bottle’s concentration. For example:
• 600mg in 30mL --> Each 1mL contains 20mg of CBD.
• 1200mg in 30mL --> Each 1mL contains 40mg of CBD.
• 3000mg in 30mL --> Each 1mL contains 100mg of CBD.
Everyone is different and everyone’s internal balance system (Homeostasis) is different. Some people are slightly “out of balance” and other people are very much “out of balance.” Some people are very sensitive to substances and others are less responsive. There is no magic number, no formula, and no test to determine how “out of balance” you are. The good news is we have a great method to discover your “happy place” or “optimal serving.” We call this process “micro-servings.”
Please Note: The amount of body fat, duration and severity of condition, GI/Liver function, individual biochemical makeup, and endocannabinoid balance may affect outcome.
ATTENTION: Some medications may interact or impact serving size. Please call 412-421-4996 or 412-586-4678 to speak to a Pharmacist about any medications you are taking.
Potential Minimal Side Effects: Dry mouth, low blood pressure, lightheadedness, potential feelings similar to dizziness and fatigue. - Source: https://medlineplus.gov/druginfo/natural/1439.html
Safety Concerns: Cannabidiol doses of up to 300 mg daily have been taken by mouth safely for up to 6 months. Higher doses of 1200-1500 mg daily have been taken by mouth safely for up to 4 weeks. – Source: https://medlineplus.gov/druginfo/natural/1439.html
NOTE: Many people feel more mentally alert and focused using CBD so we suggest starting the initial serving in the AM for at least a week before adding a second PM serving.
Help us further CBD Research! Fill out our questionnaire and help us collect important data about CBD and your experience! Click here to fill out our CBD Questionnaire.
Not recommended for use in pregnant women or women who are breastfeeding as there is not enough reliable information on these groups. Please consult your physician before use.
For more information on CBD please consult the following paper from the National Institutes of Health: PACHER P, BÁTKAI S, KUNOS G. The Endocannabinoid System as an Emerging Target of Pharmacotherapy. Pharmacological reviews. 2006;58(3):389-462. doi:10.1124/pr.58.3.2.
And the World Health Organization’s paper, “CANNABIDIOL (CBD) Pre-Review Report Agenda Item 5.2 Expert Committee on Drug Dependence, Thirty-ninth Meeting, Geneva, 6-10 November 2017.
Another useful resource is the National Institutes of Health’s US National Library of Medicine, https://medlineplus.gov/druginfo/natural/1439.html